Please use this identifier to cite or link to this item: http://repository.aaup.edu/jspui/handle/123456789/1517
Title: Advances in targeting central sensitization and brain plasticity in chronic pain
Authors: Bazzari, AH$AAUP$Palestinian
Bazzari, FH$AAUP$Palestinian
Keywords: Nociception
Neuropathic pain
Phantom limb
Hyperalgesia
Neurostimulation
Neuromodulation
Virtual reality
Cognitive therapy
Rehabilitation
Issue Date: 1-Apr-2022
Publisher: The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Citation: Bazzari, A.H., Bazzari, F.H. Advances in targeting central sensitization and brain plasticity in chronic pain. Egypt J Neurol Psychiatry Neurosurg 58, 38 (2022).
Abstract: Maladaptation in sensory neural plasticity of nociceptive pathways is associated with various types of chronic pain through central sensitization and remodeling of brain connectivity. Within this context, extensive research has been conducted to evaluate the mechanisms and efficacy of certain non-pharmacological pain treatment modalities. These include neurostimulation, virtual reality, cognitive therapy and rehabilitation. Here, we summarize the involved mechanisms and review novel findings in relation to nociceptive desensitization and modulation of plasticity for the management of intractable chronic pain and prevention of acute-to-chronic pain transition.
URI: http://repository.aaup.edu/jspui/handle/123456789/1517
Appears in Collections:Faculty & Staff Scientific Research publications

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