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http://repository.aaup.edu/jspui/handle/123456789/622
Title: | The Behavior of Ciprofloxacin at a DNA Modified Glassy Carbon Electrodes |
Authors: | nizam diab ibrahim abu-shqair, $Other$Palestinian radi salim, $Other$Palestinian mohammad al-subu, $Other$Palestinian |
Keywords: | ciprofloxacin modified electrode DNA - modified electrode anodic stripping voltammatry differential pulse voltammetry |
Issue Date: | 2014 |
Publisher: | International Journal of Electrochemical Science |
Abstract: | The voltammetric behavior of ciprofloxacin was investigated using cyclic voltammetry and differential-pulse anodic stripping voltammetry at bare glassy carbon (GC) electrodes and DNA-modified glassy carbon (DNA-GC) electrodes. For both types of electrodes, only one anodic irreversible wave was observed. A comparison between the current responses for the ciprofloxacin at the modified DNA-GC and unmodified GC electrodes, it was showed that the DNA-modified electrode exhibits a significant enhancement of the voltammetric current response with a better peak shape. Also, the interaction of ciprofloxacin with DNA was studied by using cyclic voltammetry technique at (DNA-GC) electrodes,which showed a weak interaction with a binding constant (K) = 2.89 x 105 M-1. A linear relationship between the peak current and ciprofloxacin concentrations was observed in the range 1.0–10.0 ?M, with a slope a detection limit of 0.117 ?M, with r = 0.998, and 1.0 ?M. |
URI: | http://repository.aaup.edu/jspui/handle/123456789/622 |
Appears in Collections: | Faculty & Staff Scientific Research publications |
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