Post-Operative Pain Management of Urgent General Surgeries: A Comparison Between Single Paracetamol &Ketamine plus Paracetamol in Tubas Governmental Hospital. A Randomized Control Trial Study رسالة ماجستير

Abstract

Many patients suffer from severe pain after general surgeries like inguinal hernia, where the traditional pain management methods (giving patients 1g of Perflgan (Paracetamol)) are usually insufficient to relieve the pain which increases the need for more doses of analgesia and sometimes the need for a combination of analgesia agents. Moreover, this not only increases the analgesia consumption but also may increase the possibility of post-operative complications. Therefore, we shall be using a combination of Paracetamol and ketamine to achieve full pain relief and patient satisfaction, comparing it to using Paracetamolsingly and thus prove that it is more effective. The present study aims to compare patients’ post-operative pain by using ketamine plus Paracetamol vs Paracetamol singly among urgent general surgery patients. This study is a true experimental randomized, controlled, prospective study, conducted at Tubas Turkish Government Surgical Hospital in Tubas, Palestine. The study is conducted on 60 male and female patients undergoing urgent general surgeries under the department of general snuggeries. American Society of Anesthesiologists (ASA) physical status I and II patients, Ages ranging from 15 to 60 years. The sample is divided into two groups (30 patients each): Paracetamol 1g group, Paracetamol 1g plus ketamine group. Ketamine has proven to be an effective analgesic drug, which came with less opioid consumption, prolonged analgesia, and more pain relief satisfaction. V The findings of the study revealed that the K group is established to be more effective than the NK Group in terms of postoperative analgesia with reduced rescue analgesic requirements. The study recommended using ketamine in post-operative urgent general surgeries either singly or adjunct to opioids such as Pethidine, to apply ketamine in ED to achieve better pain relief for several procedures such as fractures or dislocations.