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http://repository.aaup.edu/jspui/handle/123456789/612| Title: | Spectroscopic Studies on the Binding of Some Fluoroquinolones with DNA |
| Authors: | ibrahaim abu-shqair nizam diab radi salim mohammad al-subu |
| Keywords: | fluoroquinolone DNA binding Intercalation UV - Visible Methods |
| Issue Date: | 2013 |
| Publisher: | Asian Journal of Applied Sciences |
| Abstract: | UV-visible spectroscopic methods were used to study the interaction of some fluoroquinolones with calf-thymus DNA. The binding constants of drug-DNA complexes were evaluated and the nature of binding of these drugs with DNA were elucidated. The results suggested that fluoroquinolones bind to DNA through an electrostatic mode of interaction with partial intercalation. |
| URI: | http://repository.aaup.edu/jspui/handle/123456789/612 |
| Appears in Collections: | Faculty & Staff Scientific Research publications |
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