How Much is Stable the Bonding of CAD-CAM Implant-Supported All-Ceramic Restorations to Titanium Bases Clinically? A Systematic Review

Abstract

Abstract: The rapid advancement of digital technologies and the introduction of new ceramic materials have largely attributed to the notable transition from metal-ceramic to all-ceramic implant restorations bonded to Ti-bases. The purpose of this review was to evaluate all clinical studies reporting on the bond stability between CAD-CAM implant-supported all-ceramic restorations and Tibases. The review was directed according to the PRISMA guidelines to answer the focused question “How much is the stability and durability of the resin bond between implant-supported fixed CAD-CAM ceramic restorations and Ti- bases clinically?”. The PubMed, Google Scholar, and Cochrane databases were investigated to identify related clinical studies. Human studies assessing at least 10 patients restored with implant-supported fixed CAD-CAM ceramic restorations luted to prefabricated Ti-bases with a mean follow-up of at least 1 year and published in an English-language up to Sep. 2024 were included. The restorations could be single crown, fixed dental prosthesis, or full-arch fixed prosthesis. The search yielded 5,190 records; of these, 59 full-text articles were evaluated based on eligibility criteria. Ultimately, 40 studies were included. All 40 studies demonstrated low debonding rates from Ti-bases for single copings, multi-unit fixed dental prostheses, and full arch zirconia prostheses. Based on the limited evidence available, different factors were blamed for the debonding incidence, such as Ti-base height, geometry, luting agent, inadequacy of passive fit and biomechanical patient- and prosthesis-related factors. CAD-CAM implant-supported all-ceramic restorations bonded to Ti-bases demonstrated relatively high bond stability during observation period ranging from 1 to 7.5 years. More well-designed clinical research with longterm observation periods is highly recommended.