Spectroscopic Studies on the Binding of Some Fluoroquinolones with DNA

Please use this identifier to cite or link to this item: http://repository.aaup.edu/jspui/handle/123456789/612

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DC Field	Value	Language
dc.contributor.author	ibrahaim abu-shqair	-
dc.contributor.author	nizam diab	-
dc.contributor.author	radi salim	-
dc.contributor.author	mohammad al-subu	-
dc.date.accessioned	2020-02-05T07:02:11Z	-
dc.date.available	2020-02-05T07:02:11Z	-
dc.date.issued	2013	-
dc.identifier.uri	http://repository.aaup.edu/jspui/handle/123456789/612	-
dc.description.abstract	UV-visible spectroscopic methods were used to study the interaction of some fluoroquinolones with calf-thymus DNA. The binding constants of drug-DNA complexes were evaluated and the nature of binding of these drugs with DNA were elucidated. The results suggested that fluoroquinolones bind to DNA through an electrostatic mode of interaction with partial intercalation.	en_US
dc.publisher	Asian Journal of Applied Sciences	en_US
dc.subject	fluoroquinolone	en_US
dc.subject	DNA binding	en_US
dc.subject	Intercalation	en_US
dc.subject	UV - Visible Methods	en_US
dc.title	Spectroscopic Studies on the Binding of Some Fluoroquinolones with DNA	en_US
dc.type	Article	en_US
Appears in Collections:	Faculty & Staff Scientific Research publications

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