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Title: Functionalised electrode array for the detection of nitric oxide released by endothelial cells using different NO-sensing chemistries
Authors: joshua oni, $Other$Other
alain pailleret, $Other$Other
sonnur isik, $Other$Other
nizam diab
ina radtke, $Other$Other
rea bl?chl, $Other$Other
michael jackson, $Other$Other
fethi bedioui, $Other$Other
wolfgang schuhmann, $Other$Other
Issue Date: 2004
Publisher: Analytical and Bioanalytical Chemistry
Abstract: In a preliminary study aimed at developing strategies for the simultaneous detection of various biologically important molecules, a procedure is described that allows the electrochemical detection of nitric oxide (NO) released by a population of human umbilical vein endothelial cells (HUVEC) by using an array of electrodes comprising three individually addressable electrodes. Each electrode in the array was modified with a different NO-sensitive electrocatalyst, thereby demonstrating the possibility of modifying the individual electrodes in an array with different sensing chemistries. This study opens a doorway to the development of arrays of electrodes for the simultaneous detection of multiple analytes in a complex environment by suitably tailoring the sensitivity and selectivity of each electrode in the array to a specific analyte in the test medium.
Appears in Collections:Faculty & Staff Scientific Research publications

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