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|Title:||Functionalised electrode array for the detection of nitric oxide released by endothelial cells using different NO-sensing chemistries|
|Authors:||joshua oni, $Other$Other|
alain pailleret, $Other$Other
sonnur isik, $Other$Other
ina radtke, $Other$Other
rea bl?chl, $Other$Other
michael jackson, $Other$Other
fethi bedioui, $Other$Other
wolfgang schuhmann, $Other$Other
|Publisher:||Analytical and Bioanalytical Chemistry|
|Abstract:||In a preliminary study aimed at developing strategies for the simultaneous detection of various biologically important molecules, a procedure is described that allows the electrochemical detection of nitric oxide (NO) released by a population of human umbilical vein endothelial cells (HUVEC) by using an array of electrodes comprising three individually addressable electrodes. Each electrode in the array was modified with a different NO-sensitive electrocatalyst, thereby demonstrating the possibility of modifying the individual electrodes in an array with different sensing chemistries. This study opens a doorway to the development of arrays of electrodes for the simultaneous detection of multiple analytes in a complex environment by suitably tailoring the sensitivity and selectivity of each electrode in the array to a specific analyte in the test medium.|
|Appears in Collections:||Faculty & Staff Scientific Research publications|
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