Electrochemical reduction of Metronidazole and its Determination in Pharmaceutical dosage forms using D.C. Polarography

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DC Field	Value	Language
dc.contributor.author	ali z. abu zuhri
dc.contributor.author	m.s. suleliman
dc.contributor.author	s. khalil
dc.date.accessioned	2020-02-10T11:39:12Z	-
dc.date.available	2020-02-10T11:39:12Z	-
dc.date.issued	1986
dc.identifier.uri	http://repository.aaup.edu/jspui/handle/123456789/763	-
dc.description.abstract	A simple d.c. polarographic method has been developed for the determination of metronidazole in dosages forms. In Robinson - Britton buffer (pH 4.38) and in presence of 1.60 × 10^?3 % Triton X-100, the drug produced a well defined 4-electron polarographic wave followed by another wave of about half the height of the first wave. The current is proportional to the concentration and permits the drug to be determined by d.c. polarography in the concentration range 5.0 × 10^?5 -7.0 × 10^?4 M. Results obtained by the proposed method are in excellent agreement with that provided by the USP-XX method. A rapid, sensitive and accurate polarographic method for the determination of metronidazole in the tablets which are produced locally is proposed.
dc.publisher	Analytical Letters
dc.subject	D.C. Polarography
dc.subject	Metronidazole Determination
dc.subject	Pharmaceutical Tablets
dc.title	Electrochemical reduction of Metronidazole and its Determination in Pharmaceutical dosage forms using D.C. Polarography
dc.type	Article
Appears in Collections:	Faculty & Staff Scientific Research publications

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