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Title: Molecular markers for Phlebotomus papatasi (Diptera Psychodidae) and their usefulness for population genetic analysis
Authors: omar hamarsheh
wolfgang presber
amer aljawabreh
ziad abdeen
ahmad amro
gabriele sch?nian
Keywords: Phlebotomus papatasi
Sand flies; Genetic markers
Population genetics
Issue Date: 2009
Publisher: Transactions of the Royal Society of Tropical Medicine and Hygiene
Abstract: Three molecular typing tools: multilocus microsatellite typing, cytochrome b sequence analysis and internal transcribed spacer 2 (ITS2) sequence analysis, were evaluated for their usefulness in inferring the population structure of Phlebotomus papatasi sand flies. ITS2 sequence analysis did not prove suitable for inferring phylogenetic and population genetic relationships across P. papatasi sand flies. Microsatellite markers showed high resolution in differentiating globally distributed P. papatasi populations, whereas cytochrome b sequence analysis provided insight into the relationships between closely related populations from the Mediterranean. Population structure, differentiation and demographic history among P. papatasi are important for understanding patterns of dispersal in this species and for planning appropriate control measures.
Appears in Collections:Faculty & Staff Scientific Research publications

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